Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This really is an impurity connected to bortezomib, a proteasome inhibitor Utilized in the cure of numerous myeloma. Its synthesis or review is crucial for guaranteeing the purity and protection of the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor from the synthesis of abiraterone acetate, a drug used in the procedure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-ten-1): A critical compound within the synthesis of imatinib, a drug that targets unique sorts of cancer, which include chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are typically intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their examine is vital for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is employed to deal with CAS NO. 848133-35-7 breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist Utilized in the treatment of breast cancer. Many intermediates help in the synthesis of this drug.
Paclitaxel Side Chain Acid (CAS NO. 949023-16-9): This intermediate is Utilized in the synthesis of paclitaxel, a chemotherapy drug productive in managing cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug used in the treatment of colorectal cancer and smaller cell lung cancer.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is involved in the synthesis of adamantane derivatives, 4 which have different programs, like antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-4 to manage blood sugar stages.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-one): This compound is linked to the synthesis of assorted gluconic acid derivatives, which happen to be Utilized in food stuff, pharmaceutical, and industrial purposes.
Canagliflozin Intermediate 2: A precursor while in the synthesis of canagliflozin, a medication utilised to control sort 2 diabetes by inhibiting sodium-glucose co-transporter 2 (SGLT2).